Mercedes-Benz S-Class Sedan (W221) · S-Class

W221

Presence restored — the S-Class regains its authority.

Production
2005–2013
Built
547,599
Body
Sedan
Chassis
W221
Mercedes-Benz S-Class Sedan (W221) (W221)

The W221 answered the criticism levelled at its predecessor by putting the muscle back — pronounced rear haunches, a deeper grille and a cabin that made the W220 look tentative.

Introduced in August 2005, it offered the M272 V6, M273 V8 and M275 V12, later joined by the M278 biturbo V8 and, from AMG, the naturally aspirated M156 6.2 and the M157 5.5 biturbo. It was the first Mercedes-Benz with Night View Assist, and the S 400 HYBRID of 2009 was the world’s first production car to use a lithium-ion battery.

A comprehensive 2009 facelift carried it through to June 2013, alongside long-wheelbase, Pullman and Guard derivatives built at Sindelfingen.

W221 interior
Cabin of the W221.

Every model.

11 model designations across 2005–2013 — engines, transmissions and series codes for the W221.

ModeloAños-modeloChasisMotorTransmisiónTotal
S 3502005–2013221M 272 / M 2767G-TRONIC
S 4502005–2013221M 2737G-TRONIC
S 5002005–2013221M 273 / M 2787G-TRONIC
S 6002005–2013221M 2755G-TRONIC
S 250 CDI2010–2013221OM 6517G-TRONIC
S 320 CDI2005–2013221OM 6427G-TRONIC
S 350 BlueTEC2009–2013221OM 6427G-TRONIC
S 420 CDI2005–2013221OM 6297G-TRONIC
S 400 HYBRID2009–2013221M 272 + electric7G-TRONIC
S 63 AMG2005–2013221M 156 / M 157AMG SPEEDSHIFT MCT 9G
S 65 AMG2005–2013221M 2755G-TRONIC
W221 side profile
Studio profile of the W221 — the proportions that defined this generation.
W221 rear three-quarter view
Rear three-quarter view of the W221.